BDBM28661 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic acid::CHEMBL38943::GW 501516::GW-501516::GW1516::GW501516

SMILES Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YDBLKRPLXZNVNB-UHFFFAOYSA-N

Data  5 KI  13 IC50  89 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 28661   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  2.20E+3nMAssay Description:Transactivation of Gal4-fused human PPARalpha expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  4.40E+3nMAssay Description:Transactivation of Gal4-fused human PPARgamma expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  9.5nMAssay Description:Transactivation of Gal4-fused human PPARdelta expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  76nMAssay Description:Transactivation of Gal4-fused mouse PPARdelta expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair