BDBM50163015 (2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL193692

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCC(c3ccccc3)c3ccccc3)ncnc12

InChI Key InChIKey=TUGMXIURLRAWSS-UMCMBGNQSA-N

Data  21 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163015   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [125I]-AB-MECA binding to human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  49.9nMAssay Description:Binding affinity to A2A adenosine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  50nMAssay Description:Inhibition of [3H]-R-PIA binding to human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1AR measured after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  510nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2AR measured after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  510nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  540nMAssay Description:Inhibition of [125I]-AB-MECA binding to rat Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataEC50:  485nMAssay Description:Agonist activity at recombinant human A2BAR expressed in CHO cells assessed as stimulation of cAMP formation preincubated for 30 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed