BDBM50017702 1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-((E)-3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine(flunarizine)::CHEMBL30008::CHEMBL539027::Flunarizine::NCGC00018102::cid_6365505

SMILES Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=SMANXXCATUTDDT-QPJJXVBHSA-N

Data  2 KI  22 IC50  5 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017702   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataIC50:  228nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataIC50:  290nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed