BDBM50446481 CHEMBL3110004::US10011611, TMP269::US10722597, Compound TMP-269

SMILES FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=HORXBWNTEDOVKN-UHFFFAOYSA-N

Data  16 KI  38 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446481   

TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL

LigandBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)Copy SMILESCopy InChI

Affinity DataIC50: >4.30E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDB

In DepthDetails ArticlePubMed
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