BDBM17660 (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid::2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid::CHEMBL279956::Quisqualate::Quisqualate, L::quisqualic acid

SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O

InChI Key InChIKey=ASNFTDCKZKHJSW-REOHCLBHSA-N

Data  38 KI  2 IC50  21 EC50

PDB links: 24 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 17660   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi:  250nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi:  420nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  2.50E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  4.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR3 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Mus musculus)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1a in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  1.64E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in humanMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  750nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataEC50:  150nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in humanMore data for this Ligand-Target Pair