BDBM50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax

SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI Key InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N

Data  115 KI  52 IC50  4 Kd  15 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50005835   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  376nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 2A receptor from cloned Human membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 2A receptor in GF6 cells transfected with human 5-HT2A gene labeled with [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding activity radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  7.94E+3nMAssay Description:Binding activity radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed