BDBM50420954 CHEMBL2088089

SMILES Cc1cc(Nc2nc(NCCc3cccnc3)ncc2Br)[nH]n1

InChI Key InChIKey=UOHJGIQDKUHCQV-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420954   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50420954(CHEMBL2088089)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of human FGFR1 phosphorylation expressed in COS1 cells after 1 hr by immunoblottingMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50420954(CHEMBL2088089)
Affinity DataIC50:  501nMAssay Description:Inhibition of recombinant N terminal GST-tagged human FGFR1 (456 to 765) expressed in baculovirus infected Sf21 cells after 40 mins by caliper mobili...More data for this Ligand-Target Pair