BDBM50236939 CHEMBL2333945

SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(cc1)C(=O)NNC(=O)c1ccccc1

InChI Key InChIKey=FYIBXBFDXNPBSF-UHFFFAOYSA-N

Data  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236939   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  5.00E+4nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed