BDBM50446481 CHEMBL3110004::US10011611, TMP269::US10722597, Compound TMP-269
SMILES FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1
InChI Key InChIKey=HORXBWNTEDOVKN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50446481
Affinity DataKi: 19nMAssay Description:Inhibition of human HDAC9 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19.4nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43.3nMAssay Description:The inhibitory activity of panobinostat dissolved in DMSO and that of the HP-β-CD panobinostat adduct (prepared as described in Example 1) were ...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of HDAC9 (unknown origin) using fluorogenic HDAC class 2a as substrate measured after 1 to 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23.2nMAssay Description:Inhibition of human recombinant HDAC9 using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair