BDBM50134443 CHEMBL3746457

SMILES Fc1ccc(nc1)N1CCn2nc(COc3ccccc3)cc2C1=O

InChI Key InChIKey=CNYVJDHTGDPUBS-UHFFFAOYSA-N

Data  1 IC50  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134443   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50134443(CHEMBL3746457)
Affinity DataEC50:  126nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50134443(CHEMBL3746457)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed