BDBM50238419 CHEMBL4060134

SMILES Cn1cnc(c1)C(=O)N1CCN(CC1)C(=O)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1

InChI Key InChIKey=YFNNDVKJUPAWSW-UHFFFAOYSA-N

Data  13 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238419   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238419(CHEMBL4060134)
Affinity DataIC50: <5.01E+3nMAssay Description:Binding affinity to PARP1 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238419(CHEMBL4060134)
Affinity DataIC50: <2.00E+3nMAssay Description:Inhibition of human PARP1 using biotin-histone as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed