BDBM50172079 CHEMBL3809489
SMILES Nc1nc(Nc2ccc3CC[C@@H](CCc3c2)N2CCCC2)nn1-c1cc2CCCc3ccccc3-c2nn1
InChI Key InChIKey=KXMZDGSRSGHMMK-VWLOTQADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50172079
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh
Curated by ChEMBL
University of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human partial length FLT3 D835Y mutant (Q580 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh
Curated by ChEMBL
University of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system using poly [Glu, Try] 4:1 as substrate in presence of [ga...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh
Curated by ChEMBL
University of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair