BDBM50172079 CHEMBL3809489

SMILES Nc1nc(Nc2ccc3CC[C@@H](CCc3c2)N2CCCC2)nn1-c1cc2CCCc3ccccc3-c2nn1

InChI Key InChIKey=KXMZDGSRSGHMMK-VWLOTQADSA-N

Data  33 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172079   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild-type human partial length MTOR (L1382 to W2549 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed