BDBM315477 US10172858, Table 1.1::US10172858, Table 1.22

SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12

InChI Key InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N

Data  3 KI  18 IC50  6 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315477   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Nestl�

Curated by ChEMBL
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataIC50:  5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed