BDBM33201 2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione::5,8-dihydroxy-2-methyl-1,4-naphthoquinone::5,8-dihydroxy-2-methylnaphthalene-1,4-dione::MLS001048870::SMR000387073::cid_271296

SMILES CC1=CC(=O)c2c(O)ccc(O)c2C1=O

InChI Key InChIKey=YKPXIWHBRBFRQM-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33201   

TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of TrxR1 in human HL60 cells incubated for 24 hrs by endpoint insulin reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  700nMAssay Description:Inhibition of NADPH-reduced rat TrxR1 assessed as suppression of DTNB reduction incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed