BDBM31064 4-(2-furanyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine::4-(2-furyl)-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine::4-(2-furyl)-2-mesyl-6-(trifluoromethyl)pyrimidine::4-(furan-2-yl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine::MLS000044646::SMR000022590::cid_3237865

SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccco1

InChI Key InChIKey=DYLWYHLPRCPPQD-UHFFFAOYSA-N

Data  12 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31064   

TargetToll-like receptor 8(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM31064(4-(2-furanyl)-2-methylsulfonyl-6-(trifluoromethyl)...)
Affinity DataIC50:  2.90E+3nMAssay Description:Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed