BDBM50507816 Bms-986165::Deucravacitinib
SMILES [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC
InChI Key InChIKey=BZZKEPGENYLQSC-FIBGUPNXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50507816
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK2 in human TF1 cells assessed as decrease in EPO-induced STAT5A phosphorylation incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK2 in human whole blood assessed as decrease in TPO-induced STAT5 phosphorylation in plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fluorescein labeled probe binding to human recombinant JAK2 JH1 domain incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair