BDBM50258268 CHEMBL4059831::US11419874, Example 21

SMILES CC[C@@H](NC(=O)c1cnn2cc(C)cnc12)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=CXEGBNQZVKLHTO-OAHLLOKOSA-N

Data  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258268   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258268(CHEMBL4059831 | US11419874, Example 21)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cell expression system using [3H]cGMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed