BDBM33201 2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione::5,8-dihydroxy-2-methyl-1,4-naphthoquinone::5,8-dihydroxy-2-methylnaphthalene-1,4-dione::MLS001048870::SMR000387073::cid_271296

SMILES CC1=CC(=O)c2c(O)ccc(O)c2C1=O

InChI Key InChIKey=YKPXIWHBRBFRQM-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33201   

TargetEukaryotic translation initiation factor 4 gamma 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  1.03E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of TrxR1 in human HL60 cells incubated for 24 hrs by endpoint insulin reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50: >7.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFemale germline-specific tumor suppressor gld-1(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  5.58E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50:  700nMAssay Description:Inhibition of NADPH-reduced rat TrxR1 assessed as suppression of DTNB reduction incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCore protein(Hepatitis C virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)
Affinity DataIC50: >4.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay