BDBM50484703 CHEMBL1945164
SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(N(C)C)c3c2)c1F
InChI Key InChIKey=RBRLMIRWHYZLCE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50484703
Affinity DataIC50: 650nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair