BDBM50010462 CHEBI:78825::CHEMBL3264002::US11147816, RO5126766-(CH5126766)::US11701360, R05126766::US20230270730, Compound ref-5::US20230382863, Compound avutometinib
SMILES CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
InChI Key InChIKey=LMMJFBMMJUMSJS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50010462
TargetMitogen-activated protein kinase kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ikena Oncology
US Patent
Ikena Oncology
US Patent
Affinity DataKd: 2.22nMAssay Description:Table 11: The experiments were performed on Biacore S200 (Cytiva). Biotinylated, unphosphorylated MEK1 was diluted to 0.1 uM by SPR buffer C (20 mM T...More data for this Ligand-Target Pair