BDBM50140172 CHEBI:3962::CHEMBL140::Curcumin::US20240131036, Example 8::US9409845, Table 1, Compound 21: curcumin
SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI Key InChIKey=VFLDPWHFBUODDF-FCXRPNKRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50140172
Affinity DataKd: 3.79E+5nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to alpha-synuclein preformed fibrils (unknown origin) expressed in Escherichia coli BL21(DE3) cells incubated for 30 mins by spectro...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to alpha-synuclein oligomer (unknown origin) expressed in Escherichia coli BL21(DE3) cells incubated for 30 mins by spectrofluoromet...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to alpha-synuclein LMV 100 kDa (unknown origin) expressed in Escherichia coli BL21(DE3) cells incubated for 30 mins by spectrofluoro...More data for this Ligand-Target Pair
Affinity DataKd: 6.50E+3nMAssay Description:Binding affinity to alpha-synuclein LMV 50 kDa (unknown origin) expressed in Escherichia coli BL21(DE3) cells incubated for 30 mins by spectrofluorom...More data for this Ligand-Target Pair
Affinity DataKd: 6.43E+4nMAssay Description:Binding affinity to human NTCP assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human DYRK1A assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human CLK1 assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair