BDBM50430793 6-aza-PAT::CHEMBL2334756

SMILES CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)[C@H]2CC[C@@H](C3)N2C2COC2)cc1

InChI Key InChIKey=WLQPHPRJRBGPBN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430793   

TargetSerine/threonine-protein kinase mTOR(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430793BDBM50430793(6-aza-PAT | CHEMBL2334756)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as inhibition of phosphorylation of (GFP)-4-EBP1 protein after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430793BDBM50430793(6-aza-PAT | CHEMBL2334756)
Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of human CYP3A4 preincubated for 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed