BDBM102575 US8536172, I-24

SMILES CS(=O)(=O)N[C@H]1CC[C@H](Nc2nccc(-n3ccc4c(N5CCN(C(=O)CN)CC5)cccc43)n2)CC1

InChI Key InChIKey=XQCXNDUXSUPQGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102575   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102575BDBM102575(US8536172, I-24)
Affinity DataIC50: 77.7nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102575BDBM102575(US8536172, I-24)
Affinity DataIC50: 477nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent