BDBM120992 US11547697, Compound 77::US9682141, 77

SMILES Nc1nc2cc(ccc2o1)-c1ccc2ncc(C#N)c(Cl)c2c1

InChI Key InChIKey=IPYOSIQUEIDRBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120992   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandChemical structure of BindingDB Monomer ID 120992BDBM120992(US9682141, 77 | US11547697, Compound 77)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandChemical structure of BindingDB Monomer ID 120992BDBM120992(US9682141, 77 | US11547697, Compound 77)
Affinity DataIC50: 1.00E+3nMAssay Description:The compounds described herein can be tested against recombinant mTOR (Invitrogen) in an assay containing 50 mM HEPES, pH 7.5, 1 mM EGTA, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent