BDBM136493 US8865726, 124

SMILES Cc1ccnc([C@H]2COC(=O)N2c2ccn3ncc(-c4ccc(-c5nc[nH]n5)cc4)c3n2)c1

InChI Key InChIKey=DOVVUTBJXBDGIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136493   

TargetSerine/threonine-protein kinase mTOR(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 136493BDBM136493(US8865726, 124)
Affinity DataIC50: 11.4nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent