BDBM136508 US8865726, 139

SMILES OP(O)(=O)OCn1cnc(n1)-c1ccc(cc1F)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(F)cn1

InChI Key InChIKey=SFRVMXJAKYOXEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136508   

TargetSerine/threonine-protein kinase mTOR(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 136508BDBM136508(US8865726, 139)
Affinity DataIC50: 11.3nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent