BDBM140238 US8906911, 47

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(Cl)c(c1)C#N

InChI Key InChIKey=LPLKMCDXZLNWBC-XXXJXAHKSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140238   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140238(US8906911, 47)
Affinity DataKi:  77nM ΔG°:  -9.01kcal/mole IC50:  49.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent