BDBM142736 US9682141, 569::US9682141, 572

SMILES CC(C)(N)C(=O)N1CCN(CC1)c1cnc2ccc(nc2n1)-c1ccc2oc(N)nc2c1

InChI Key InChIKey=VVNHDWMDKZCENW-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 142736   

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 100nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Briefly, the assay is a time resolved FRET assay that indirectly measures PIP3 product formed by the activity of a PI3-K. The kinase reaction is perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandChemical structure of BindingDB Monomer ID 142736BDBM142736(US9682141, 572 | US9682141, 569)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent