BDBM15949 Aminopyridine-Based Inhibitor 29::N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-piperidin-1-ylacetamide::N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(piperidin-1-yl)acetamide

SMILES CCOc1nc(NC(=O)CN2CCCCC2)cc(N)c1C#N

InChI Key InChIKey=CWUXAOWJNDMVEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15949   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15949BDBM15949(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(piperi...)
Affinity DataIC50: 510nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15949BDBM15949(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(piperi...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed