BDBM172483 US9675593, 427

SMILES CN1C(=O)COc2cccc(-c3cn(-c4ccc(OC(F)(F)F)cc4)c(=O)cc3C)c12

InChI Key InChIKey=NJKQOCIUKKIHLS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172483   

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM172483(US9675593, 427)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
US Patent