BDBM172717 US9090657, 24

SMILES CC(C)[C@@H]1NC(=O)[C@H](CCC(C)=O)[C@H](O)[C@@H](C)[C@@H](O)\C=C\C=C\C[C@H](OC(=O)C2CCCN(N2)C(=O)[C@H](Cc2cc(O)cc(F)c2)NC1=O)C(\C)=C\C=C\C(=O)N1CCCCO1

InChI Key InChIKey=CFLBTKFHBBDVKC-RROFBZPUSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 172717   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50:  0.310nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50:  4.30E+3nMpH: 7.3 T: 2°CAssay Description:To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50:  1.80E+3nMpH: 7.3 T: 2°CAssay Description:To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile salt export pump(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50:  1.23E+4nMT: 2°CAssay Description:To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50: >5.00E+4nMT: 2°CAssay Description:To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:To assess the inhibition of the P-glycoprotein (Pgp/MDR1) transporter, an in vitro ATPase assay from Cyprotex was used. MDR1MDCK cells obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50: >5.00E+4nMT: 2°CAssay Description:To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent