BDBM178313 US9120812, 98

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(nc2OC(C)(C)CN(CC)C(=O)c12)N1CCOC[C@@H]1C

InChI Key InChIKey=FINNGPDNYBZHBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178313   

TargetSerine/threonine-protein kinase mTOR(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 178313BDBM178313(US9120812, 98)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 178313BDBM178313(US9120812, 98)
Affinity DataIC50: 1.14E+3nMpH: 7.5Assay Description:The test uses a lucifeurerin/luciferase system to measure the concentration of ATP and its consumption during the enzymatic reaction. The test is per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent