BDBM178430 US9120812, 215

SMILES CCN1CC(C)(C)Oc2nc(nc(-c3ccc(NC(=O)Nc4ccc(cc4)C(=O)N(C)CCN(C)C)cc3)c2C1=O)N1CCOC[C@@H]1C

InChI Key InChIKey=BUJFZUKAKHWOLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178430   

LigandChemical structure of BindingDB Monomer ID 178430BDBM178430(US9120812, 215)
Affinity DataIC50: 37nMpH: 7.5Assay Description:The test uses a lucifeurerin/luciferase system to measure the concentration of ATP and its consumption during the enzymatic reaction. The test is per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 178430BDBM178430(US9120812, 215)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent