BDBM19560 (2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-methylphenyl)formamido]-3-(pyridin-3-yl)propanamide::arylaminoethyl amide, 5n

SMILES COc1ccc(NCCNC(=O)[C@H](Cc2cccnc2)NC(=O)c2cccc(C)c2)cc1

InChI Key InChIKey=JMUXXPOJEDRJNE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19560   

TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19560((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  673nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19560((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  3.71E+3nM ΔG°:  -7.70kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19560((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed