BDBM200996 US9540364, example 8

SMILES CC(CO)(CO)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@H](CO)[C@H]3O)[nH]c2cc1Cl

InChI Key InChIKey=COOWPIOEGGFBPI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200996   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200996(US9540364, example 8)
Affinity DataEC50:  5nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent