BDBM226872 US20260008758, Compound 181

SMILES Cn1c(=O)oc2ccc(-c3ccc(C[C@@H](C#N)NC(=O)C[C@@H](N)Cc4cccs4)cc3)cc21

InChI Key InChIKey=JTEKXNCRBFBIFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226872   

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 226872BDBM226872(US20260008758, Compound 181)
Affinity DataIC50: 15nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 226872BDBM226872(US20260008758, Compound 181)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent