BDBM229808 ((R)-2-(difluoromethyl)-5-fluoro-1-((R)-5-(pyridin-2-yl)-2,3-dihydro-1H-indene-2-carbonyl)indoline-6-sulfonamide)::US12522582, Example 127

SMILES NS(=O)(=O)c1cc2c(cc1F)C[C@H](C(F)F)N2C(=O)[C@@H]1Cc2ccc(-c3ccccn3)cc2C1

InChI Key InChIKey=ATDAYSHEHZWJHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 229808   

TargetCarbonic anhydrase 2(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 229808BDBM229808(((R)-2-(difluoromethyl)-5-fluoro-1-((R)-5-(pyridin...)
Affinity DataIC50: 2.46E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 229808BDBM229808(((R)-2-(difluoromethyl)-5-fluoro-1-((R)-5-(pyridin...)
Affinity DataIC50: 4.19E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent