BDBM229810 (S)-5-fluoro-1-((1R,2S)-1-methyl-5-(pyridin-2-yl)-2,3-dihydro-1H-indene-2-carbonyl)-3-(trifluoromethyl)indoline-6-sulfonamide::US12522582, Example 138

SMILES C[C@H]1c2ccc(-c3ccccn3)cc2C[C@@H]1C(=O)N1C[C@@H](C(F)(F)F)c2cc(F)c(S(N)(=O)=O)cc21

InChI Key InChIKey=CTYUDPMHQKCBER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 229810   

TargetCarbonic anhydrase 2(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 229810BDBM229810((S)-5-fluoro-1-((1R,2S)-1-methyl-5-(pyridin-2-yl)-...)
Affinity DataIC50: 1.97E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 229810BDBM229810((S)-5-fluoro-1-((1R,2S)-1-methyl-5-(pyridin-2-yl)-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent