BDBM23846 5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19d

SMILES COc1ccc-2c(CCc3ccc(Oc4cccc(CCc5ccc-2c(OC)c5)c4)cc3)c1

InChI Key InChIKey=GLTFSJARKJFXDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23846   

TargetAlpha-glucosidase MAL32(Saccharomyces cerevisiae)
University of Tokyo

LigandPNGBDBM23846(5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...)
Affinity DataIC50: >3.00E+4nMpH: 7.0 T: 2°CAssay Description:The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23846(5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...)
Affinity DataIC50:  4.60E+4nMAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23846(5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...)
Affinity DataIC50:  2.50E+4nMAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed