BDBM2589 1-Hydroxy-3,4-bis(3-indolyl)-2,5-pyrroledione::1-hydroxy-3,4-bis(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 11

SMILES O=C1C(c2c[nH]c3ccccc23)=C(c2c[nH]c3ccccc23)C(=O)N1O

InChI Key InChIKey=STOYHVQKKWVYFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2589   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandChemical structure of BindingDB Monomer ID 2589BDBM2589(1-Hydroxy-3,4-bis(3-indolyl)-2,5-pyrroledione | 1-...)
Affinity DataIC50: 2.89E+4nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed