BDBM270574 (S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N6-ethyl-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-6

SMILES [2H]C(N(CC)c1ccc2ncnc(NCC(C)(C)C)c2c1)(c1cn(nn1)C1CC1)c1ccc(F)cc1

InChI Key InChIKey=BTTKRWWCCQEAES-QPTZSGNNSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270574   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270574((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...)
Affinity DataEC50:  4.23E+3nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270574((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...)
Affinity DataIC50:  276nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent