BDBM272937 (S)-2-((1-(2-amino-4- fluorobenzo[d]thiazol- 6-yl)-7,8,9,10- tetrahydro-6-oxa- 2,10a- diazacycloocta[cd]- inden-4- yl)oxy)propanamide::US10065970, Compound 242::US10435414, Compound 242

SMILES C[C@H](Oc1cc2OCCCCn3c(nc(c1)c23)-c1cc(F)c2nc(N)sc2c1)C(N)=O

InChI Key InChIKey=VUMIRXHJUKHXBP-JTQLQIEISA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272937   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM272937((S)-2-((1-(2-amino-4- fluorobenzo[d]thiazol- 6-yl)...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM272937((S)-2-((1-(2-amino-4- fluorobenzo[d]thiazol- 6-yl)...)
Affinity DataKi: <0.0200nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent