BDBM275430 1-[7-(hydroxymethyl)-1- (tetrahydro-2H-pyran-4-ylmethyl)- 1H-pyrazolo[3,4-c]pyridin-5-yl]-3-::US9884048, Example 309

SMILES C[C@@H](NC(=O)Nc1cc2cnn(CC3CCOCC3)c2c(CO)n1)c1ccccc1

InChI Key InChIKey=FUFAMSZXARAVQL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275430   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275430(1-[7-(hydroxymethyl)-1- (tetrahydro-2H-pyran-4-ylm...)
Affinity DataAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent