BDBM276327 (S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-2,2-diethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 281::US20260098038, Example 281

SMILES CCC1(CC)Cc2cc(-c3ccc(C4CC4)cc3)ccc2C1NC(=O)O[C@H]1CN2CCC1CC2

InChI Key InChIKey=LIPANDNMULHPDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276327   

TargetMannosyl-oligosaccharide glucosidase(Human)
Yuhan

US Patent
LigandChemical structure of BindingDB Monomer ID 276327BDBM276327((S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-2,2-...)
Affinity DataIC50: 0.600nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Yuhan

US Patent
LigandChemical structure of BindingDB Monomer ID 276327BDBM276327((S)-quinuclidin-3-yl (5-(4-cyclopropylphenyl)-2,2-...)
Affinity DataIC50: 0.600nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent