BDBM276428 (S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-6-fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate::US12522602, Example 382::US20260098038, Example 382

SMILES COc1ccc(OC)c(-c2cc3c(cc2F)C(NC(=O)O[C@H]2CN4CCC2CC4)C(C)(C)C3)c1

InChI Key InChIKey=VWDRCNCNTSFCMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276428   

TargetMannosyl-oligosaccharide glucosidase(Human)
Yuhan

US Patent
LigandChemical structure of BindingDB Monomer ID 276428BDBM276428((S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-6-fl...)
Affinity DataIC50: 0.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Yuhan

US Patent
LigandChemical structure of BindingDB Monomer ID 276428BDBM276428((S)-quinuclidin-3-yl (5-(2,5-dimethoxyphenyl)-6-fl...)
Affinity DataIC50: 0.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent