BDBM27963 3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-((1r,4r)-4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-6-yl)-1-((trans)-4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::3-{2-[(2-chlorophenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1-[4-(morpholin-4-yl)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL251732::substituted benzimidazole, 8
SMILES Nc1ncnc2n(nc(-c3ccc4nc(Cc5ccccc5Cl)[nH]c4c3)c12)[C@H]1CC[C@@H](CC1)N1CCOCC1
InChI Key InChIKey=DZHMNRMMNFEUNL-MEMLXQNLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 27963
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 664nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair