BDBM27967 ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexyl]piperazine-1-carboxylate::substituted pyrazolopyrimidine, 12

SMILES CCOC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)n1nc(-c2ccc3nc(Cc4ccccc4OC)[nH]c3c2)c2c(N)ncnc12

InChI Key InChIKey=IWSFWGQTDDJZPR-RQNOJGIXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27967   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27967(ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]...)
Affinity DataIC50:  309nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27967(ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]...)
Affinity DataIC50:  270nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27967(ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed