BDBM288344 US10087187, Compound 34::US10087187, Compound 35
SMILES Cc1nc2c(cc(nn2c1Nc1cccc(c1C)C(F)(F)F)N1CCOCC1)-c1ncc[nH]1
InChI Key InChIKey=GGGQATCGIAEYIP-UHFFFAOYSA-N
Data 10 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 288344
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 2.60nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 49nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 81nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 912nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 2.24E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 2.29E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Affinity DataKd: 4.68E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKd: 6.92E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair