BDBM289928 1-[1-(2-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-2,3-dihydro-benzofuran-3-yl}-ethyl)-piperidin-4-yl]-pyrrolidin-2-one (68)::US9573957, Example 68

SMILES O=C1CCCN1C1CCN(CCC2COc3cc(Oc4ccc(-c5ccn[nH]5)cn4)ccc32)CC1

InChI Key InChIKey=XFNHMTKRPWLMGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289928   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 289928BDBM289928(1-[1-(2-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-2...)
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent